Fecal microbiota transplant (FMT), also known as a stool transplant, is the process of transferring fecal bacteria and other microbes from a healthy individual into an unhealthy individual. It is an effective treatment for Clostridioides difficile infection; for recurrent cases, FMT is more effective than the antibiotic vancomycin alone, and may improve the outcome after the first infection.
Facts
FAQs
Is the evidence for fecal microbiota transplant settled?
One review called its application not well established.
Not fully, according to one published review. Its abstract says fecal microbiota transplantation has shown to be effective and safe in recurrent Clostridium difficile infections, but that very few pragmatic studies have demonstrated its efficacy and safety, so its application is not well established. The authors called for robust studies, both observation and experiment, to establish its effectiveness and safety in treating recurrent Clostridium difficile infection.
Connections
Sources
1. Wikipedia
Wikipedia contributors, Wikimedia FoundationHistory sectionQuote, History section
The first use of FMT in western medicine was published in 1958 by Ben Eiseman and colleagues, a team of surgeons from Colorado, who treated four critically ill people with fulminant pseudomembranous colitis (before C. difficile was the known cause) using fecal enemas, which resulted in a rapid return to health.
Wikidata: Fecal Microbiota Transplant
Wikidata Q2121103, class allow-list match (w-wdresolver-0926)View the Source Fecal microbiota transplant (Wikipedia)
https://en.wikipedia.org/wiki/Fecal_microbiota_transplant, lead sectionQuote, https://en.wikipedia.org/wiki/Fecal_microbiota_transplant, lead section
Fecal microbiota transplant (FMT), also known as a stool transplant, is the process of transferring fecal bacteria and other microbes from a healthy individual into an unhealthy individual.
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