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Corvalol

Pharmacological Therapy

Corvalol is a tranquilizer based on the barbiturate phenobarbital, combined with the ethyl ester of alpha-bromoisovaleric acid, peppermint oil, valerian root extract, and hop extract, and it is popular in Eastern Europe and former Soviet territories. It was developed in the USSR in 1960 as an analogue of the German drug Valocordin and is similar to it in composition and therapeutic action. Corvalol is widely available without a prescription in Eastern European and former Soviet countries, but it is illegal to import into the United States because phenobarbital is a controlled substance there; the Ukrainian pharmaceutical company Farmak holds exclusive trademark rights to it in Ukraine and several other Eastern European countries, while multiple manufacturers distribute it in Russia.

Facts
Classification
Status
Standard of Care 1
Origin Year
1960 2
FAQs

Why can Corvalol be bought without a prescription in some countries but not imported into the United States?

It contains phenobarbital, which is a controlled substance in the United States.

The difference comes from its main active ingredient, phenobarbital. In Russia Corvalol is sold without prescription, even though ordinary phenobarbital tablets are sold strictly by doctor's prescription. In the United States phenobarbital is a DEA Schedule IV substance, and it is illegal to import Corvalol. The article also notes that in some Eastern European countries it is believed safe enough to use in recommended doses without prescription, while its label warns of overdose from accumulation when used frequently and in large doses. This is a record of the legal position, not medical advice.
Connections

Treats

Source Corvalol (Wikipedia)
Sources
1. Wikipedia
Wikipedia contributors, Wikimedia Foundation
2. Corvalol (Wikipedia)
  • Developed in the USSR in 1960 as an analogue of Valocordin, article intro
  • https://en.wikipedia.org/wiki/Corvalol, lead section
    Corvalol (Корвалол, Corvalolum, Korvalol) is a tranquilizer based on the barbiturate phenobarbital and containing various natural components, such as herb valerian (Valeriana officinalis) root, as well as peppermint oil Mentha piperita and hop extract Humulus lupulus, popular in Eastern Europe and the former Soviet Union as a heart medication.
  • Treats: Hypertension, Article text, use for
    as a part of complex treatment of hypertension
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